Abstract: Abstract: Wave run-up is a key parameter in determining the crest elevation of earth embankments, and it is considerably affected by the wave reduction effect of protection slope. Smooth concrete prefabricated block is widely used in the slope protection of embankments. However, its wave reduction effect is relatively poor. To solve this problem, 3 new kinds of prefabricated blocks were designed to improve the wave reduction effect by increasing the roughness coefficient of the prefabricated block, including concave and embedded regular hexagon type prefabricated block, Z type prefabricated concrete block and embedded quadrangle type prefabricated hollow block. According to the formula in Handbook of hydraulic structure design, the thickness of prefabricated block was calculated, and then a laboratorial physical model experiment was performed in a wave flume for the slope protection and wave dissipation. Nine tests were carried out under 3 water depths (23.6, 30.6 and 37.15 cm) and 3 wave periods (1.5, 1.875 and 2.5 s). In the experiment, waves were produced by a wave maker, and the wave run-up was measured by a photogrammetric method. The wave reduction effects of the 3 new kinds of prefabricated blocks were assessed by the reduction ratio of the wave run-up compared with the smooth concrete prefabricated block. Additionally, the values of the 3 new kinds of prefabricated blocks' roughness coefficient were proposed. The experiment results showed that, compared with the smooth concrete prefabricated block, the 3 kinds of prefabricated blocks proposed in this paper had obvious inhibiting effects on wave run-up. The concave and embedded regular hexagon type prefabricated block had the most inhibiting effect, followed by the Z type prefabricated concrete block and embedded quadrangle type prefabricated hollow block. Their wave run-up decay rates (the reduction ratio of the new designs to the smooth concrete prefabricated block) were 35.0%, 30.2% and 26.23%, respectively, and corresponding roughness coefficients were 0.76, 0.77 and 0.79, respectively. Finally, the economic benefits of the 3 kinds of new designed prefabricated blocks were analyzed in this paper. It was mainly divided into 2 parts, the revetment concrete amount with the same thickness, and the extent of crest elevation reduction by the wave reduction effects. According to the comprehensive comparison and analysis, the concave and embedded regular hexagon type prefabricated block consumed less concrete amount, which decreased by 17.13% compared with the smooth concrete prefabricated block, and wave run-up was more reduced. For example, if the wave run-up of the smooth concrete prefabricated block was 1.0 m, the concave and embedded regular hexagon type prefabricated block would be 0.65 m, the Z type prefabricated concrete block would be 0.70 m, and the embedded quadrangle type prefabricated hollow block would be 0.74 m. Consequently, considering the effect of revetment wave and economic benefit, the concave and embedded regular hexagon type prefabricated block is the best choice in the slope protection and has popularization value and development prospects.