Abstract: Abstract: Biogas slurry has a low nutrients concentration but with a large volume, which also contains antibiotics, heavy metals and other pollutants. These issues are obstacles needed to be overcome in the harmless treatment and resource utilization of biogas slurry. The present research have reviewed the properties of the biogas slurry resources and its problems in utilization, so what is mainly discussed in this paper are the high-value treatments and resource utilizations from the viewpoints of concentration technology of biogas, and the removal of antibiotics and heavy metals from the biogas slurry or concentrated biogas slurry. The results indicate that, the high-value treatment of biogas slurry through combining thereverse osmosis membrane concentration with solar energy negative pressure concentration, the removal of antibiotics in biogas slurry by advanced oxidation technologies including Fenton reagent, and the removal of heavy metals in biogas slurry through biological method or heavy metal collector method, which may be three important directions for the research of harmless treatment and resource utilization of biogas slurry. This review could provide references for the research and exploitation of biogas slurry in the future.