Abstract: Grain cleaning is the core technology of peanut harvest. Therefore, in the process of peanut harvesting, how to enhance operation fluency and efficiency, and to ensure technical indicators such as low loss rate of cleaning, low impurity rate of peanut pods, has been a difficult technical problem of whole-feed peanut combine harvester. In order to settle the above difficulties, a cleaning device of tangential flow and whole-feed peanut combine harvester was designed, realizing the grain winnowed combined with screened, one-time large and small sundries clearance, sieve surface unencumbered. The cleaning device of tangential flow and whole-feed peanut combine harvester consisted of pole sieve, multi-stage elastic sieve, behind sieve, straw-shaking wheel, eccentric sleeve, main fan, auxiliary fan. The vibrating sieve consisted of pole sieve, multi-stage elastic sieve, behind sieve. Pole sieve was above the vibrating sieve. Multi-stage elastic sieve and behind sieve were below the vibrating sieve. Combined with existed mechanism advantages, a crank-rocker mechanism which consisted of the vibrating sieve and swinging arm was brought forward. In the application of cleaning device of tangential flow and whole-feed peanut combine harvester, there are many problems such as high impurity rate of peanut pods, high loss rate of cleaning, agricultural film tangles, and debris blockage. Utilizing kineto-statics method, in this paper, we researched relative motion of grain on the sieve surface, analyzed limiting conditions of grain upglide, downglide, jump from sieve surface, and determined the key motion parameter in theory. Vibration acceleration of vibrating sieve was 17.5-24.5 m/s2. Amplitude of vibrating sieve was 7.5-17.5 mm. Vibration frequency of vibrating sieve was 5-9 Hz. Utilizing D'Alembert's principle, in this paper, we also researched sieve force under alternating loads, determined the important structure parameter of sieve. Cleaning device was matched onto the whole-feed combine and a lot of tests were carried out in the field. Loss rate of cleaning and impurity rate of peanut pods were taken as the evaluation indicator of cleaning quality. The key factors affecting cleaning quality were researched by field experiment in this paper. A scheme of orthogonal test, which included 3 factors and 3 levels, was designed. That key factor included amplitude, vibration frequency and revolving speed of main fan. The value range of amplitude and vibration frequency was based on the preceding theoretical analysis. The value range of revolving speed of main fan was based on single factor experiment. The experimental results showed that significant order for multi-factors affected on cleaning quality was: revolving speed of main fan, amplitude, vibration frequency. Within the scope of the 95% confidence coefficient, revolving speed of main fan was extremely significant for cleaning quality, amplitude and vibration frequency were significant for cleaning quality. The optimal parameter combination was that revolving speed of main fan was 2 100 r/min, amplitude was 12.5 mm, vibration frequency was 9 Hz. Under the above optimal parameters, field experiments were carried out, loss rate of cleaning was 5.03% and impurity rate of peanut pods was 5.39%. The operation of cleaning device is fluent, almost no agricultural film tangles and debris blockage. The research results provide theoretical basis for design and parameter optimization of whole-feed peanut combine harvester and cleaning device.