Abstract: Cultivated land being an essential natural resource, has been increasingly occupied in the last 60 years with the acceleration of urbanization. It is necessary to be careful in land use, in order to ensure food security and human existence. In addition, the quality degradation of cultivated land has seriously threatened to food security due to the misuse of land. Slope farmland, one type of cultivated land, is widely distributed in the plateau and mountain areas in the central and western China. Scientific quality evaluation of slope farmland is closely related to local food security and ecological environment, further to implement national protection schemes, such as the “Trinity” of quantity, quality and ecology. However, there are some features of slope farmland, such as wide distribution, large slope, soil erosion, frequent seasonal drought, low soil quality, to make accurate evaluation difficult. The evaluation index and model are also lacking. Taking the slope farmland in Yunnan as a research area, this study aims to construct a quality evaluation system of slope farmland based on the framework of “element demand regulation”. The 30 m × 30 m grid (pixel) was selected as an evaluation unit for the comprehensive weight. The quality of slope farmland was evaluated quantitatively, together with its characteristics of spatial distribution. The results showed that: 1) Index system of the Minimum Data Set (MDS) in quality evaluation of slope farmland consisted of 14 indexes, including the effective thickness of soil layer, arable layer thickness, bulk density of soil, soil texture, pH value of soil, organic matter, effective phosphorus, available potassium, accumulated temperature (≥10 ℃), field regularity, contiguity, amount of rainfall, assurance rate of irrigation, and field slope. 2) Slope farmland Integrated Fertility Index (SIFI) was distributed between 0.36 and 0.81, with an average value of 0.59. Most evaluation units of SIFI was less than 0.6, showing a significant difference (P<0.05). The SIFI size relationship between five types of soil in slope farmland were ranked in order: Lateritic red earths, Red earths, Purplish soils, Yellow earths, Yellow-brown earths. SIFI increased with the elevation in the range of 0-1 000 m, while decreased larger than 1 000 m, indicating the variation of SIFI was related to the range of elevation. 3) The quality of slope farmland can be Grade 6, 5, 7 and 4, according the national standard. Specifically, the quality of slope farmland was relatively high Grade 4 and 5 at the southern border, central, southeast, and western Yunnan, whereas, northeast and northwest Yunnan indicated low Grade 6 and 7. The Lorenz curve of quality grade showed a pattern of “S-type” distribution in different regions, indicating a low grade in Yunnan province. This finding can provide a scientific basis to improve the quality evaluation system of slope land, thereby to efficiently implement geological regulation of slope farmland.