银杏黄酮苷提纯工艺研究

    Optimum Extracting Technology of Flavonoid Glycosides in GBE

    • 摘要: 根据黄酮苷的物性选择丙酮,正丁醇,正丙醇,乙酸乙酯为萃取剂。单因素实验优选出正丙醇为萃取黄酮苷的主萃取剂。对其进行改性,通过单因素实验和正交实验优化出:水∶正丙醇=1∶25为萃取黄酮苷的较佳萃取剂。T=25℃,t=10 min,固液比=15∶1(g/100 mL)为其最佳萃取工艺参数。最后得到纯度>50%,得率>80%的总黄酮苷产品。为后续提纯分离打下较好的基础。

       

      Abstract: According to flavonoides' material properity, normal butyl alcohol, npropanol and ethyl acetate are chosen solvent. The optimum extracting conditions of flavonoids from GBE, which the ginkgolide was extracted(ginkgolide contents<0.3%). The results showed that at 25℃, the ratio of solvents of water to npropanol is equal to 1∶25, the ratio of solid to modified liquid is equal to 15∶1, the extracted time is 10 minutes, the total flavonoides of extraction was more than 50%, the obtained ratio of the total flavonoides in GBE is more than 80%.

       

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