Abstract: A compound drink powder was made from Lycium barbarum and Hippophae rhamnoides through the processes including extracting juice, clarifying, concentrating, making-up and centrifugal spray drying. The results showed that process of obtaining extractive Lycium barbarum juice was: breaking→thermal treatment→pressing. The mixed solution of 0.05% L-AA and 0.02% NaHSO₃ is used for the protective coloration of Lycium barbarum juice. And the drying additive was maltodextrine. Its quantity was 80% of dissoluble solid content of juice. The ingredient is defined as follows: the mass ratio of Lycium barbarum to Hippophae rhamnoides was 6∶2, aspartame 0.95%, sugar 4.0% and citric acid 0.1%.