Abstract: Based on the support of GIS, the regional agricultural climate database and crop production database, the method for calculating the region-based crop potential productivity was established, by means of the factor attenuation of solar radiation, temperature, water, soil, fertilization, irrigation and the social factor. The crop potential yield per unit area, potential coefficiency, total potential productivity, and the developing advantage of crop production were analyzed qualitatively in Jiangsu Province. The results show that from north to south, the developing advantage of crop potential productivity increases gradually. Taken crop into account, cotton has the biggest developing pttential, rape has the smallest and grain is in the middle. In terms of economic zones, the developing advantage of grain, oil-bearing products and cotton is different. For grain, the Tai Lake Region>the region along the Yangze River>the coastal region>the Nanjing-Zhenjiang-Yangzhou Region>the Lianghuai Region>the Xuzhou-Lianyungang Region; for cotton, the Tai Lake Region>the coastal region>the region along the Yangze River>the Nanjing-Zhenjiang-Yangzhou Region>the Xuzhou-Lianyungang Region>the Lianghuai Region; for oil-bearing products, the Tai Lake Region>the Nanjing-Zhenjiang-Yangzhou Region>the region along the Yangze River>the coastal region> the Lianghuai Region>the Xuzhou-Lianyungang Region. In the same economic region, the developing advantage of grain, oil-bearing products and cotton is also different. In the Xuzhou-Lianyungang region, cotton> grain >oil-bearing products; in the Lianghuai Region, cotton is the most advantageous, grain and oil-bearing products are relatively similar; in the Nanjing-Zhenjiang-Yangzhou Region, oil-bearing products are the most advantaged, grain and cotton are similar. In the region along the Yangze River, grain, oil-bearing products and cotton have similar development advantage. In the Tai Lake Region, cotton is the most advantageous, grain and oil-bearing products have similar developing advantage; in the coastal region, cotton> grain >oil-bearing products.