Abstract: The orthogonal experiment was conducted to study the application of FA Handilong, a kind of drought-resistant agent for fruit tree. Its effect on the growth, capability against drought, fruit quality and yields of fruit were investigated. The results show: FA Handilong, could increase its drought-resistant potential of the fruit tree and its yield increased by 4.88%～7.32%; The economic benefit increased by 15654.00～23559.00 yuan per hectare. The average fruit weight could be increased using FA Handilong by 4.2%～8.4%. The fruit quality was also improved. Compared with the condition of full irrigation, the water use efficiency was also improved, and the irrigative water was saved by 487.5 m³ per hectare. The best frequency and time of the application of FA Handilong were discussed.