Abstract: Acetate of potato starch can be produced by reaction between the starch and acetic anhydride in alkaline solution, then crosslinking acetated starch can be obtained by crosslinking reaction between acetated starch and crosslinking agent. The optimum technology for producing crosslinking acetated starch was achieved through orthogonal experiments under different conditions, which was as follows: reaction temperature 35℃, pH 11, reaction time 2 h, 2% crosslinking agent. The crosslinking acetate of potato starch produced by using the optimized technology has better stability, staling resistance, phase-resistant isolation, etc. than the raw potato starch. Besides, the properties of potato starch and crosslinking acetate of potato starch were compared and analyzed.