Abstract: Taking the lettuce as material, the authors designed the different bottom shapes of NFT cultivation bed to study the effects on the growth and quality of the lettuce. The results indicate that the different bottom shapes of NFT cultivation bed has significant influence on the aboveground fresh and dry weight of lettuce, but has no significant influence on the quality of lettuce. And the bottom shape whose straight-cut section is a scalene triangle, has significant influence on the expansion and the yield of lettuce. In NFT, the cultivation bed with no-cloth cover has significant influence on the yield of lettuce. Taken the quality and economic benefits into accounts, the bottom shape as(6+14)×4 is better.