Abstract: Biodegradation of the refractory organic pollutants by white rot fungi has been widely studied. The results demonstrate that series of special enzymes secreted by white rot fungi or other methods related to the fungi can degrade such pollutants to CO₂ and H₂O. This article mainly concerned the biologic characteristics of the white rot fungi and enzymes secreted by the fungi. The degradation mechanisms of the refractory organics pollutant by the secreted enzymes were expatiated, the methods of increasing the degradation activities of the white rot fungi were discussed, and the disadvantage of the white rot fungi using in practice and the research direction in the future were summarized. It comes to conclusion that the fungi are very useful to degrading many refractory organic compound and controlling environmental pollutants.