Abstract: The chemical control is an important input during the course of the growth of cotton, for a great scale region, the date of chemical control usually refers to some solid season, regardless of the spatial difference among cotton fields. Under the framework of precision farming, this paper recommends using geostatistical image texture to monitor the growth cndition of cotton, guiding the spray of chemical medicine. Comparing with tradition method based on vegetation index, although it could not calculate the concrete value of cotton growth condition, it could precisely abtain the spatial distribution of growth condition, what is more, it could identify the cotton field which is at the vigorous growth stage, and which is not able to be distinguished by the method based on vegetation index, so it is a better method towards guiding to chemical control of cotton.