Abstract: The effects of different air speeds(0.0(CK), 0.4(A-1), 1.0(A-2), 2.2 m/s(A-3)) in greenhouse on muskmelon were analyzed. The results showed that the optimal air speed was treatment A-2. Comparing with CK, 21.68% more leaf area, 63.06% more LAI, 120.32% higher Gs, two days earlier maturation, 24.43% more yield, 11.07% higher total sugar were obtained; while the TSS and protein increased with the air speed. Comparing with CK, A-3 is 13.88% more TSS, 3.6% more protein; the Reduce Sugar decreases with the air speeds, CK is 10.53% more than A-3. The Pulp of melon and vitamin C have no significant difference. It proves that the effect of different air speed in greenhouse on muskmelon was significant and the best air speed is 1.0 m/s.