Abstract: The complicated topography of mountainous area makes local natural resources obvious spatial differentiation. Taking Qixia City as a case, eco-suitability and sensitivity were analyzed at county level, based on altitude, soil texture, soil thickness and other eco-factors, after extracting landuse pattern, aspect, slope from digital elevation model (DEM), and quantitative simulating mean annual accumulated temperature (≥0℃), mean annual precipitation. Then the whole area was divided into four parts, namely: optimizing development zone, major development zone, limited development zone, and prohibited development zone according to their suitability, sensitivity and vertical heterogeneity respectively. And some corresponding developing and managing measures were put forward, finally. This research provides a precise approach for landscape ecology optimization in mountainous area at county level.