Abstract: The membrane fouling and the flux decrement are impediment to the application of membrane technology. To understand the absorption and deposition of fiber, protein and lignin in hydrolysate of steam-exploded wheat straw by xylanase on ceramic membrane surface and the influences on microfiltration flux, the equations of deposition resistance and absorption resistance were established based on the experimental data, and the correlation coefficient between the linear model predicted values and experiment results of deposition resistance was 0.9914. Meanwhile, three kinds of nonlinear absorption resistance model, which were based on saturation model, modificatory pearl growth model and pearl growth model, were established. The correlation coefficient between these nonlinear models predicted values and experiment results of absorption resistance were 0.9931, 0.9980 and 0.9982, respectively. Based on these results, differential equation model of flux was established, the correlation coefficient between predicted values and experiment results of flux was 0.9963 and the correlation coefficient between predicted values and reduplicate results was 0.9838. The results showed that the models’ simulation data were in good agreement with the experimental data of flux decrement.