Abstract: Regional integrated food security is an important part of national general food security. For the regional integrated food security, establishment of risk index system for early warning is the premise for risk early warning and effective precaution. In this paper, the conceptions of integrative food security were defined (i.e. food quantity security, food quality security and food sustainable supply security), a framework of index system for early warning was established, and instructions on the calculation of each index were achieved. Meanwhile, a case study was carried out in Hunan Province. The results showed that in the 14 years of 1992-2005, the integrated food security in Hunan Province was at a level of slight alarm, in which the food quantity security was at a stable no-alarm level, the food qualitative security at a relatively serious situation due to its 9 years of medium alarm and 5 years of heavy alarm; and the tendency of food sustainable supply security in a positive process for its 1 year of medium alarm, 5 years of slight alarm and the rest years of no-alarm. Thus the quality security should be regarded as the key issue of risk prevention of integrated food security in Hunan Province, at the same time the sustainable supply security should be strengthened.