Abstract: In order to quantitatively evaluate the effects of wind tunnel central speed, stubble height, vegetation coverage and their interaction on wind erosion of conservation tillage farmland, uniform experimental design and wind tunnel testing in -situ field were adopted, and multi-factor experiment of anti-wind erosion effects of conservation tillage farmland was completed. Conservation tillage farmland anti-wind erosion model was established using partial least-squares regression (PLSR) theory. The results showed that effects of each factor on sediment transport rate in proper order were center wind speed, vegetation coverage and stubble height; those on retention rate in proper order were stubble height, vegetation coverage and center wind speed; for both sediment transport rate and retention rate, interaction regulations between factors were same i.e. stubble height × vegetation coverage, center wind speed × vegetation coverage and center wind speed × stubble height based on the order of the main effect standard regression coefficients. The results showed that anti-wind erosion mechanism of conservation tillage farmland was not only affected by single factor, but also closely related with the interactions among central speed, stubble height and vegetation coverage.