Abstract: In the light of the characteristics of information management of emergency prevention and control for severe epidemic disease, an emergency commanding platform for animal disease in Beijing was established, including overall layout, structure of technical system, function, database, and design and exploitation. In the paper, a series of critical techniques including operation flow pattern, logical frame for emergency disposal, and comprehensive decision-making model were researched. Application of seamless bonding technology for Flex controls and ArcObjects components in the system was proposed; some key issues including analysis of epidemic focus, determination of epidemic spot, epidemic area, threatened area, intersection blocking, epidemic monitoring, harmless disposal, disinfection, slaughter, emergency immunization and lifting of the blockade were resolved. Based on the platform, the aim of information and integration of emergency command for major animal disease in Beijing was achieved. The platform can provide timely and accurate information for comprehensive judgment of actual prevention and control situation and scientific decision-making, as well as fast and great support to emergency command for severe animal epidemic disease for Beijing.