Abstract: Prepared series of La2AXB1-XO4 catalysts and soot particles were mixed, then were placed in fixed-bed continuous flow reaction system to do simulation tests to evaluate catalytic activities. It was found that La2Cu0.9Fe0.1O4 showed better PM oxidation characteristic, which was consistent with the H2-TPR experiment results. TG-DTA tests also indicated solid reliability of the experiment results. Temperature-programmed tests were taken on cordierite and SiC catalytic substrate respectively. The results suggested that soot particles on the two kinds of substrate showed similar oxidation characteristics in temperature window 200-350℃. Engine bench tests also validated that La2Cu0.9Fe0.1O4 could oxidize diesel emission soot particles efficiently. Computational model was established to simulate DPF soot loading and regeneration. The model was verified by engine bench test results, which suggested that the model was able to describe diesel soot particles oxidation process precisely.