Abstract: In order to research the influence of different refrigerated transport enclosure for the environment uniformity, 3D turbulence models of the enclosure in and out from the top and enclosure in from the top and out from the bottom and differential pressure enclosure designed by South China Agricultural University were built, and the software FLUENT, SIMPLE algorithm and wall function method was used to do numerical calculation for the three kinds of enclosure structure models when they were no-load or full load, to analyze the wind and cloud vector diagram of the airflow patterns in the structures. Through different section of comparative analysis, it showed that the flow field in differential pressure enclosure was more uniform than those in the two other structure whether it was no-load or full; The airflow field in enclosure in from the top and out from the bottom with cargo was more uniform than the airflow field in no-load and the enclosure in and out from the top; The wind speed gradient was larger, and the uniformity of flow distribution was general in the enclosure in and out from the top both no-load or full. The results have reference value for the optimal design?of refrigerated transport enclosure.