Abstract: Abstract: According to all the weather data of cities and counties in Jilin Province from 2001 to 2012 publicly released by the National Weather Service, this paper took the corn as research object, and calculated the equilibrium moisture content of grain by combining the effects of temperature and relative humidity on grain storage through grain heat and humid balance theory and model, and adopted the spatial data analysis tool of GIS together with mathematical cluster analysis to delimit the ecological area for food storage in Jilin Province, which overcame the drawbacks of single factor division and provided a reliable scientific basis for grain storage safety. Jilin grain storage area can be divided into three zones: Zone Ⅰ is western plains of Jilin Province, including Baicheng, Changchun, Siping; Zone Ⅱ is in middle eastern area of Jilin Province, including Jilin, Liaoyuan, Meihekou, Tonghua and some areas of Hakusan; Zone Ⅲ is eastern mountainous region of Jilin Province, including Yanbian, Changbai and other areas. And food storage areas have different characteristics. Among three zones, ZoneⅠis located in the central and western plains of Jilin Province, which has higher temperature, smaller precipitation, smaller air relative humidity, bigger wind speed and longer sunshine hour. The climate is conducive to air circulation and suitable for grain storage. Therefore, this area is the best one among the ecological areas for grain storage in Jilin. The grain storage area should pay attention to reducing the grain temperature in the months from June to September, and mechanical cooling can be considered to solve the problem. Ecological grain storage mode should be continuous drying in medium-sized cooperatives and centralized storage of warehouse rations in this area. Zone Ⅱ is located in the Mid-eastern area of Jilin Province. Maybe due to the higher altitude, the region has higher air relative humidity, higher temperature, larger precipitation, minimum wind speed and shorter sunshine hour. This grain storage area from June to September should pay attention to ventilation, and mechanical ventilation can reduce the grain temperature. The main mode of grain storage should be small continuous drying and dry food storage in warehouse in this area. Zone Ⅲ is in the eastern mountains of Jilin Province. The climate is rather special in this region, which is east of the Sea of Japan, so climate is humid. This region is in the Changbai Mountain area and altitude is high, so this region has shorter daylight hour, higher air humidity, lower temperature, and larger precipitation and wind speed. Therefore, grain storage in this area should be considering technical measures such as mechanical ventilation and precipitation from June to September. And the main grain storage mode should be grain storage in farmers' warehouse together with precipitation, plus centralized storage of warehouse rations in this area. Equilibrium moisture content and equilibrium relative humidity are predicting trends of grain moisture, environment condition during grain storage is the determinants of changes of grain moisture content, and the appropriate treatment measures have important and extensive effect. This study analyzes the characteristics of climate in each grain storage area for appropriate method recommendation of grain storage. Dividing food storage area provides a scientific basis for scientific grain storage and grain storage security, and provides a theoretical basis for establishing applied technology and management systems according to the characteristics of China's grain storage area.