Abstract: In view of the shortcomings of the control method and technology for chassis centralized lubrication system, the principles of automatic greasing and fault detection based on single chip microprocessor technique were presented in this paper. The greasing interval time and monitoring time are set by using the monitor, the pressure in main lines is detected and the pump operating time is adjusted by using the pressure sensor in order to carry out auto-greasing timing and fault alarm function for lubrication system. The hardware circuit of control system and the flowchart of main control program for software were designed by using PIC single chip microprocessor. The results of performance test and practical application of the system indicate that the monitor has higher reliability and stability. It is significant to develop intelligent monitor in centralized lubrication system for bus chassis.